Body Fluids and Buffers provides a foundational understanding of the biochemical composition and physiological importance of body fluids. The course focuses on the properties of water as a biological solvent, the principles of pH, and the function of buffering systems in maintaining acid–base balance. It highlights how these components work together to preserve homeostasis and ensure proper physiological functioning. Through carefully curated digital resources and structured learning materials, this course reinforces the core concepts introduced in Biochemistry-I. Emphasis is placed on connecting theoretical knowledge with clinical relevance, enabling students to develop a clear and practical understanding of fluid balance and its significance in health and disease.